L-肌肽

属性

熔点	253°C
旋光率	21 ° (C=2, H2O)
敏感性	易吸潮;对空气敏感
溶解性	Soluble in 80% acetic acid (10 mg/ml), and water (1:3.1).
存贮条件	储存温度-20°C,充氩保存
密度	1.3750

描述

应用	二肽，具潜在的抗氧剂和抗糖基化活性；阻止乙醛诱导的非酶糖基化和蛋白质偶联。也是肌肽酶检测的底物。具细胞抗氧化，维持机体pH平衡，延长细胞寿命。
产品介绍	L-肌肽是一种二肽，以毫摩尔浓度出现在大脑、肌肉和眼睛的晶状体上。
生化机理	L-Carosine is a dipeptide found at millimolar concentration in brain, muscle and the lens of the eye. In model systems it is a potent antioxidant that scavenges oxygen free radicals and transition metal ions. It blocks protein-protein and protein-DNA cross-links induced by hypochlorite anions and toxic aldehydes such as acetaldehyde, formaldehyde, and malondialdehyde, the primary product of lipid peroxidation. It also inhibits nonenzymatic protein glycation induced by aldose and ketose reducing sugars and inhibits the formation of toxic advanced glycation end products (AGE). These activities make it of interest in studies of aging, atherosclerosis, Alzheimer′s disease, and the secondary effects of diabetes.
别名	β-氨基-L-丙酰组氨酸;N-β-丙氨酰-L-组氨酸 ；L-肉缩氨基酸;β-Alanyl-L-histidine; L-Ignotine; N-beta-Alanyl-L-histidine

Reaxys-RN	87671
Merck Index	1850
个人防护设备	Eyeshields,Gloves,type N95 (US),type P1 (EN143) respirator filter
RTECS	MS3080000
WGK德国	2
安全声明（欧洲）	S24/25;