喹吖因 二盐酸盐

属性

敏感性	对光线敏感
溶解性	Soluble in water (50 mg/ml with heat, yielding a clear solution), and ethanol (slightly). Insoluble in alcohol, benzene, chloroform, and ether.

描述

应用	A non-specific PLA2 inhibitor. and acetylcholine receptor antagonist
产品介绍	Quinacrine dihydrochloride is a non-specific PLA2 (phospholipase A2) inhibitor. Quinacrine, Dihydrochloride acts as an AChR (acetylcholine receptor) antagonist. Quinacrine dihydrochloride suppresses glibenclamide-sensitive K+-currents (IC50 = 4.4 μM). This compound also inhibits MAO (monoamine oxidase). Quinacrine, Dihydrochloride is an inhibitor of cPLA2, MAO-A and MAO-B.
别名	疟疾平;盐酸米帕林;奎纳克林二盐酸盐; 阿的平盐酸盐;6-氯-9-(4-二乙基氨基-1-甲基丁基)氨基-2-甲氧基吖啶二盐酸盐;米帕林 二盐酸盐; 阿的平 二盐酸盐;;6-Chloro-9-[[4-(diethylamino)-1-methylbutyl]amino]-2-methoxyacridine dihydrochloride; Acrichin dihydrochloride; Atabrine hydrochloride; Atebrin; Atebrine; Atebrine hydrochloride; Mepacrine dihydrochloride;

Reaxys-RN	4834013
Merck Index	8044
标识符号	GHS07
信号词	Warning
危害声明	H302,H315,H319,H335
警示性声明	P261,P305+P351+P338
个人防护设备	dust mask type N95 (US),Eyeshields,Gloves
RTECS	AR7875000
WGK德国	3
风险声明 (欧洲)	R22;R36/37/38;R36/37/38;
安全声明（欧洲）	S36/37/39/;
危害码（欧洲）	Xn
UN代码	2811