| 货号 | CAS号 |
|---|---|
| P103197-1g | 553-12-8 |
| P103197-250mg | 553-12-8 |
| 敏感性 | 对光敏感 |
| 溶解性 | Soluble in DMSO (10 mg/ml), ethanol (10 mg/ml), chloroform, glacial acetic acid, alcohol containing hydrochloric acid, ether containing glacial acetic acid, hydrochloric acid, dilute alkalies, aniline, and pyridine. Insoluble in disodium salts, and dipota |
| 存贮条件 | 2-8°C避光保存 |
| 应用 |
激活可溶性的鸟苷酸环化酶；荧光免疫探针。光敏剂（光动力学交联）。 · 作为原卟啉测定的标准品 · 荧光光谱分析中 · 处理细胞培养中的细胞以研究血红素介导的铁转运蛋白1的转录 |
| 产品介绍 | Protoporphyrin-9 is the key porphyrin in animal and plant cells, presenting a precursor scaffold for heme sites and other metal domains contained in metalloproteins. Iron is introduced to the porphyrin to generate heme, the primary oxygen-binding moiety found in proteins. Protoporphyrin-9 as heme is incorporated into hemoglobin, catalase, peroxidase, and certain cytochrome enzymes. Introduction of magnesium into Protoporphyrin-9 and subsequent transformations generates chlorophyll, the main light energy-gathering pigment in plants necessary for photosynthesis. Protoporphyrin-9 is also demonstrated to activate guanylate cyclase, indicating that cellular levels of Protoporphyrin-9 and heme may serve to regulate guanylate cyclase activity and tissue cyclic GMP levels. λex 402 nm, 409 nm λem 625 nm, 633 nm |
| 生化机理 | 原卟啉IX可以穿透人体红细胞并帮助它们释放氧气。它可与肌红蛋白和血红蛋白形成复合物。它可用作癌症光动力疗法的光敏剂。 |
| 别名 | 3,7,12,17-四甲基-8,13-二乙烯基-2,18-卟吩二丙酸;Kammerer’s porphyrin 蛋壳卟啉;3,7,12,17-Tetramethyl-8,13-divinyl-2,18-porphinedipropionic acid; Kammerer’s porphyrin; Ooporphyrin;Protoporphyrin-9 |
