| 应用 |
An inhibitor of cGMP-mediated processes and guanylyl cyclase, a useful stain, and a redox indicator |
| 产品介绍 |
Methylene Blue acts as a GCS (guanylyl cyclase) inhibitor, biological stain and redox indicator. Methylene Blue inhibits tau filament formation. Additionally, Methylene Blue is also reported to inhibit NOSs (nitric oxide synthase). Methylene Blue is widely used to inhibit cGMP-mediated processes. Methylene Blue has been observed to dose-dependently induce cytotoxicity in U-373 MG human astrocytoma and SK-N-MC human neuroblastoma cells. Furthermore Methylene Blue is reported to bind to the M2 subtype of muscarinic receptors in rat cardiac myocytes, and thus exhibit antimuscarinic effects on IK, ACh and ICa. Methylene Blue has also been reported to inhibit endothelium-dependent relaxation of isolated blood vessels. |
| 别名 |
亚甲蓝;品蓝;亚甲基兰;碱性蓝9;四甲基蓝;次甲基蓝;次甲基兰;亚甲兰;碱性湖蓝BB;碱性亚甲天蓝;盐基湖蓝;盐基湖蓝BB;亚甲基天蓝;3,7-双(二甲氨基)吩噻嗪-5-翁氯化物;次甲基蓝,三水;碱性亚甲蓝三水合物;亚甲蓝;Methylene Blue trihydrate; 3,7-bis(Dimethylamino)phenazathionium chloride; Basic Blue 9; Tetramethylthionine chloride; C.I. 52015 trihydrate; Basic Blue 9 trihydrate |
