| 应用 |
L-犬尿氨酸可用作吲哚胺-2,3-双加氧酶分析标准。它还可用作从培养细胞和培养基中提取和定量犬尿氨酸的标准。 |
| 产品介绍 |
L-Kynurenine is a key intermediate in the breakdown pathway of tryptophan. L-Kynurenine is a substrate of kynureninase, KMO, and KAT associated with the suppression of antitumor immune responses. It has been shown to inhibit allogeneic T-cell proliferation and to increase malignant U87 glioma cell invasion into a collagen matrix. |
| 生化机理 |
L-犬尿氨酸是-L-色氨酸降解的关键中介物，[1]通过犬尿氨酸途径形成烟酰胺腺嘌呤二核苷酸 (NAD+) 。它参与多种神经系统过程和疾病。L-犬尿氨酸是犬尿氨酸酶/犬尿氨酸水解酶底物；犬尿氨酸3-单加氧酶和犬尿氨酸-酮戊二酸转氨酶。 色氨酸降解途径的关键中间物。 |
| 别名 |
L-犬尿氨酸水合物;L-狗尿酸水合物;L-犬尿酸水合物;L-Kynurenine;^b-Anthraniloyl-L-alanine;L-2-Amino-4-(2-aminophenyl)-4-oxobutanoic acid;β-Anthraniloyl-L-alanine |
