盐酸阿糖胞苷

属性

敏感性	易吸潮
存贮条件	储存温度2-8℃

描述

生化机理	Ara-C is phosphorylated to Ara-CTP and is incorporatee into DNA. It inhibits DNA replication by forming cleavage complexes with topoisomerase I resulting in DNA fragmentation, and ultimately induces apoptosis via the PKC signaling pathway.Does not inhibit RNA synthesis. Anti-leukemia agent.
别名	1-(β-D-呋喃阿拉伯糖苷)-胞嘧啶 盐酸盐;Ara-C 盐酸盐;胞嘧啶阿拉伯糖苷 盐酸盐;阿拉伯糖胞嘧啶 盐酸盐;阿糖胞嘧啶 盐酸盐;阿糖胞苷 盐酸盐;胞嘧啶β-D-呋喃阿拉伯糖苷 盐酸盐;1-(β-D-Arabino-furanosyl)-cytosine hydrochloride; Ara-C hydrochloride; Arabinocytidine hydrochloride; Arabinosylcytosine hydrochloride; Cytarabine hydrochloride; Cytosine arabinoside hydrochloride; 1-(β-D-Arabino-furanosyl)-cytosine HCl; Cytarabine HCl

WGK德国

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