| 应用 |
1、用于在肥大细胞中肝素钠的荧光染色。
2、一种生物碱，带有弱的抗生素特性，细菌多重耐药外排泵（MDR efflux pumps）的底物。 berberine的抗微生物活性可被MDR抑制剂5´-methoxyhydnocarpin (5´-MHC)强化。Berberine调控肝癌细胞Pgp基因的表达。 |
| 产品介绍 |
一种生物碱，CAS号为633-65-8的为无水物 |
| 生化机理 |
An alkaloid with weak antibiotic properties. Substrate for MDR efflux pumps. Antimicrobial activities of berberine is potentiated by the MDR inhibitor 5′-methoxyhydnocarpin (5′-MHC). Berberine upregulates the expression of Pgp in hepatoma cells. Treatment with berberine potentially results in the reduced accumulation of chemotherapeutic drugs. |
| 别名 |
氯化黄连素水合物，小檗碱盐酸盐;C.I. 75160;盐酸黄连素;自然黄18;633-65-8;相关CAS号:2086-83-1;C.I. 75160;Natural Yellow 18 Hydrate;related CAS:2086-83-1 |
