货号 | CAS号 | 价格 |
---|---|---|
M137749-100mg | 298-81-7 | ¥39.00 |
M137749-25g | 298-81-7 | ¥2,999.00 |
M137749-5g | 298-81-7 | ¥679.00 |
M137749-1g | 298-81-7 | ¥279.00 |
M115185-20mg | 298-81-7 | ¥199.00 |
熔点 | 143-148℃ |
敏感性 | 对光敏感 |
溶解性 | Soluble in acetone, ethanol (slight), acetic acid, and chloroform (50 mg/ml). Insoluble in water. |
应用 | A potent suicide inhibitor of cytochrome P-450. |
生化机理 | 8-Methoxypsoralen is a potent tricyclic furocoumarin suicide inhibitor of CYP (cytochrome P-450). As a member of the foranocoumarins, 8-Methoxypsoralen has shown more potency than 5-MOP, 5-OH-P , DH-8-MOP and psoralen in the inhibiton of CYP2B1 (cytochrome P-450 2B1). 8-Methoxypsoralen has been shown to completely inhibit the metabolism of nicotine in vitro. The compound has been observed to inhibit the metabolism of theophylline,caffeine,hexobarbital and phenytoin. |
别名 | 花椒毒素;甲氧基补骨脂素;甲氧沙林;8-MOP;9-甲氧基呋喃并[3,2-g][1]苯并吡喃-7-酮;花椒毒内酯8-MOP;Ammoidin;Methoxsalen;Xanthotoxin;9-Methoxyfuro[3,2-g][1]benzopyran-7-one |