| 应用 |
Pizotifen (BC-105) is a potent 5-HT2 receptor antagonist, with a high affinity for 5-HT1C binding site. Pizotifen is an antidepresent 5-HT2A receptor antagonist and has the capacity to inhibit serotonin-enhanced ADP-induced platelet aggregation. |
| 产品介绍 |
Pizotifen (BC-105) 是 5-HT2 受体的有效拮抗剂，并对 5-HT1C 有高亲和力。 |
| 生化机理 |
Pizotifen is a serotonin antagonist acting mainly at the 5-HT1, 5-HT2A and 5HT2C receptors with some antihistamine activity. It is used for the prevention of vascular headache including migraine and cluster headache. |
| 别名 |
苯噻啶; 新度美安; 4-[9,10-二氢-4H-苯并[4,5]环庚烷并[1,2-b]噻吩-4-亚基]-1-甲基哌啶
;BC-105;Pizotyline;Sandomigran; 4-(9,10-Dihydro-4H-benzo[4,5]cyclohepta[1,2-b]thien-4-ylidene)-1-methylpiperidine |
