| 产品介绍 |
Tropisetron hydrochloride is a potent SR (SR-3) antagonist. It is also a selective, partial agonist at AChR α 7 (α7 nicotinic receptors). Tropisetron hydrochloride is an inhibitor of HTR3. |
| 生化机理 |
Tropisetron is a selective 5-HT3 receptor antagonist and α7-nicotinic receptor agonist with an IC50 of 70.1 ± 0.9 nM for 5-HT3 receptor.It is used mainly as an antiemetic to treat nausea and vomiting following chemotherapy, although it has been used experimentally as an analgesic in cases of fibromyalgia.? |
| 别名 |
1H-吲哚-3-羧酸-(3-endo)-8-甲基-8-氮杂双环[3,2,1]辛烷-3-基酯盐酸盐;8-甲基-8-氮杂双环[3,2,1]-3α-辛烷-1H-吲哚-3-羧酸酯盐酸盐;ICS-205,930;Navoban;Tropisetron monohydrochloride;1H-Indole-3-carboxylic acid (3-endo)-8-methyl-8-azabicyclo[3.2.1]oct-3-yl ester monohydrochloride;3-Tropanylindole-3-carboxylate monohydrochloride |
