The IonPac®ICE-AS6 ion-exclusion column is designed for fast analysis of aliphatic organic acids (including hydroxyl-substituted organic acids) and alcohols in complex or high-ionic-strength samples, including foods and beverages, biological samples, fermentation baths, industrial process liquors, and wastewaters. The ICE-AS6 column is ideally suited for most applications performed on the ICE-AS1 column.
Use the ICE-AS6 column for organic acids in complex sample matrices.
Use the ICE-AS1 column for the fast separation of organic acids.
The ICE-AS6 column provides improved peak efficiencies and selectivity for carboxylic acids and alcohols. The weakly ionized acids are separated by pKa differences, size, and hydrophobicity. Strong acid anions such as chloride, oxalate, and sulfate elute in the void and do not interfere with the quantification of the organic acids.
The ICE-AS6 column can be used with any typical strong acid eluent and a wide range of detectors, including conductivity, amperometry, photometry, and refractive index to determine aliphatic organic acids. Use the AS11 for fast analysis of organic acids and inorganic anions in well-characterized samples. Use the high-capacity IonPac AS11-HC column for organic acids and inorganic anions in complex sample matrices or uncharacterized samples.
Note: Use the Anion MicroMembrane™ Ion-Exclusion Suppressor (AMMS®ICE 300) with the ICE-AS6 column.
| IonPac ICE-AS6 Ion-Exclusion Column Specifications | |
|---|---|
| Dimensions | IonPac ICE-AS6 Analytical Column: 9×250 mm |
| Maximum operating pressure | 5.6 MPa (800 psi) |
| Mobile phase compatibility | pH 0–7 (Use eluents containing only hydronium ion as the cation. Avoid eluents containing sodium, potassium, etc.); 0–15% HPLC solvents |
| Functional group characteristics | Ion-Exchange Group: Sulfonic and carboxylic acid Hydrophobicity: Medium low |
| Capacity | 27 meq (9×250 mm analytical column) |
| Substrate characteristics | Bead Diameter: 8 µm Bead Type: Microporous Cross-Linking (%DVB): 8% |
| Column construction | PEEK with 10-32 threaded ferrule-style end fittings. All components are nonmetallic. |
Separation of low-molecular-weight organic acids using the IonPac ICE-AS6 column.
Determination of trace organic acids in grape juice using suppressed conductivity detection.
Ion exclusion allows the determination of organic acids in sulfuric acid and eliminates sulfate interference.
Determination of strongly ionized organic acids using UV detection.
| Analytical Columns | |
|---|---|
| IonPac ICE-AS6 Analytical Column | 079798 |
