应用 |
虾青素是在海藻、红酵母和许多植物和动物来源中发现的?强效类胡萝卜素抗氧化剂。动物试验表明,它可降低血糖?并改善糖尿病代谢综合征的若干指标。可改善高血型模型?的血流和血管张力。体外研究表明,它上调间隙联接蛋白? 43,可用于化学防癌。 |
生化机理 |
Astaxanthin is a potent antioxidant with antiproliferative, neuroprotective and anti-inflammatory activity. Astaxanthin protects against oxidative stress, inhibiting NF-KB, suppressing pro-inflammatory genes and suppressing production of pro-inflammatory compounds nitric oxide, prostaglandin E2, TNF-α, and interleukin-1β. Astaxanthin′s protection of cells from oxidative stress generated by TNF-α and palmitate has been shown to ameliorate insulin resistance. Astaxanthin has also been shown to be an inhibitor of PPARγ. |
别名 |
虾青素;3,3'-二羟基-beta,beta-胡萝卜素-4,4'-二酮3,3′-Dihydroxy-β,β-carotene-4,4′-dione |