应用 |
Used in Unna-Pappenheim stain to demonstrate RNA (red) in contrast to DNA (green). Also used for bacteria staining. |
产品介绍 |
Pyronin Y is a dye that intercalates and stains RNA red, and has been shown to accumulate in the mitochondria of viable cells. Multidrug-resistant (MDR) Acinetobacter baumannii studies tested inhibition of the efflux pump by measuring the intracellluar accumulation of Pyronin Y and Ethidium bromide. Research shows that at low Pyronin Y concentrations the cytostatic effect is cell arrest in the G1 phase, whereas at high concentrations the cells arrest is in the G2 and S phase. Pyronin Y has been used in combination with Alcian Blue to asses and study pulmonary diseases, and in combination with Methyl Green to stain nucleic acids in paraffin sections. Additionally Pyronin Y has been used to measure RNA in flow cytometry. |
别名 |
3,6-双(二甲基氨基)呫吨鎓氯化物,派洛宁Y, 派若宁 G, 派若宁 J;Pyronin G;Pyronin J;3,6-Bis(dimethylamino)xanthylium chloride |