Lenalidomide

属性

溶解性	Soluble in DMSO (≥52 mg/ml) at 25 °C, methanol and water (2: 1), buffered aqueous solvents, water (<1 mg/ml) at 25 °C, and ethanol (<1 mg/ml) at 25 °C.
存贮条件	储存温度-20°C

描述

应用	A Thalidomide analog known to have immunomodulatory properties
产品介绍	Lenalidomide (CC-5013)是Thalidomide的衍生物，是一种TNF-α分泌抑制剂，IC50为13 nM。
备注	Lenalidomide (Revlimid, CC-5013) is a TNF-α secretion inhibitor with IC50 of 13 nM.
生化机理	Lenalidomide is a thalidomide analog known to inhibit TNF-α secretion and possess immunomodulatory properties.
别名	来那度胺; 3-(7-氨基-3-氧代-1H-异吲哚-2-基)哌啶-2,6-二酮;Revlimid; CC-5013 ;CC5013;CC 5013;(3S)-3-(4-Amino-1-oxo-1,3-dihydro-2H-isoindol-2-yl)piperidine-2,6-dione