| 2018 | 机构 | 分数式计量数（FC） 2017 | 分数式计量数（FC） 2018 | 论文计数（AC） 2018 | FC变化 |
| 2017-2018 |
| 1 | F.Hoffmann-La Roche AG, Switzerland | 53.69 | 56.25 | 129 | 2.60% |
| 2 | IBMCorporation, United States of America (USA) | 47.7 | 40.16 | 110 | -17.60% |
| 3 | NovartisInternational AG, Switzerland | 41.55 | 29.16 | 106 | -31.30% |
| 4 | Merck& Co., Inc., United States of America (USA) | 35.1 | 28.11 | 66 | -21.60% |
| 5 | AstraZenecaplc, United Kingdom (UK) | 29.87 | 26.07 | 122 | -14.50% |
| 6 | PfizerInc., United States of America (USA) | 23.3 | 21.33 | 67 | -10.40% |
| 7 | AlphabetInc., United States of America (USA) | 9.31 | 21.09 | 56 | 121.70% |
| 8 | NipponTelegraph and Telephone Corporation (NTT), Japan | 7.11 | 16.46 | 38 | 126.70% |
| 9 | GlaxoSmithKlineplc. (GSK), United Kingdom (UK) | 16.66 | 16.41 | 78 | -3.60% |
| 10 | AmgenInc., United States of America (USA) | 14.75 | 16.13 | 49 | 7.10% |
| 11 | Bristol-MyersSquibb (BMS), United States of America (USA) | 14.54 | 15.61 | 38 | 5.10% |
| 12 | SamsungGroup, South Korea | 15.09 | 15.16 | 68 | -1.60% |
| 13 | MicrosoftCorporation, United States of America (USA) | 11.62 | 13.74 | 70 | 15.80% |
| 14 | GNSScience, New Zealand | 16.12 | 13.16 | 60 | -20.10% |
| 15 | ChinaShipbuilding Industry Corporation (CSIC), China | 7.91 | 12.27 | 188 | 52.00% |
| 16 | DowDuPontInc., United States of America (USA) | 12.78 | 11.88 | 44 | -8.90% |
| 17 | ThermoFisher Scientific Inc., United States of America (USA) | 7.62 | 11.56 | 54 | 48.60% |
| 18 | FiberHomeTechnologies Group, China | 7.28 | 10.15 | 87 | 36.50% |
| 19 | Johnson& Johnson, United States of America (USA) | 11.63 | 8.86 | 34 | -25.40% |
| 20 | BASFSE, Germany | 8.08 | 8.75 | 49 | 5.90% |
| 21 | ToyotaGroup, Japan | 7.99 | 8.53 | 24 | 4.50% |
| 22 | ExxonMobil Corporation (ExxonMobil), United States of America (USA) | 7.81 | 8.3 | 27 | 4.00% |
| 23 | RegeneronPharmaceuticals, Inc., United States of America (USA) | 4.95 | 7.96 | 17 | 57.50% |
| 24 | AbbVieInc., United States of America (USA) | 8.51 | 6.98 | 22 | -19.60% |
| 25 | BGI,China | 5.63 | 6.83 | 32 | 18.90% |
| 26 | Sanofi,France | 4.61 | 6.78 | 30 | 43.90% |
| 27 | ChinaAerospace Science and Technology Corporation (CASC), China | 4.2 | 6.56 | 42 | 52.80% |
| 28 | TakedaPharmaceutical Company Limited, Japan | 5.52 | 6.43 | 20 | 14.10% |
| 29 | FormosaPlastics Group, Taiwan | 7.52 | 6.36 | 24 | -17.10% |
| 30 | JinchuanGroup Co., Ltd., China | 3.91 | 6.03 | 30 | 50.90% |
| 31 | LeidosHoldings, Inc., United States of America (USA) | 4.21 | 5.76 | 72 | 34.00% |
| 32 | EliLilly and Company, United States of America (USA) | 9.12 | 5.63 | 28 | -39.60% |
| 33 | ScienceSystems and Applications, Inc. (SSAI), United States of America (USA) | 5.88 | 5.59 | 26 | -7.00% |
| 34 | BrukerCorporation, United States of America (USA) | 6.68 | 5.56 | 34 | -18.50% |
| 35 | Hitachi,Ltd., Japan | 4.83 | 5.5 | 24 | 11.40% |
| 36 | UCBS.A., Belgium | 3.87 | 5.24 | 14 | 32.50% |
| 37 | C.H. Boehringer Sohn AG & Co. KG (Boehringer Ingelheim), Germany | 6.34 | 5.23 | 22 | -19.20% |
| 38 | ChinaNational Petroleum Corporation (CNPC), China | 0.8 | 4.96 | 17 | 507.90% |
| 39 | NationalInstitute of Water and Atmospheric Research Ltd. (NIWA), New Zealand | 4 | 4.91 | 37 | 20.10% |
| 40 | BayerAG, Germany | 3.76 | 4.82 | 41 | 25.60% |
| 41 | ToshibaCorporation, Japan | 7.91 | 4.28 | 7 | -47.00% |
| 42 | ThalesS.A., France | 4.11 | 4.22 | 36 | 0.60% |
| 43 | HPInc., United States of America (USA) | 3.76 | 4.05 | 10 | 5.20% |
| 44 | ShanghaiJiahua Poly Battery Technology Co., Ltd., China | 0.65 | 4.03 | 12 | 507.30% |
| 45 | IonisPharmaceuticals, Inc., United States of America (USA) | 3.45 | 3.89 | 19 | 10.40% |
| 46 | MerckKGaA, Germany | 3.88 | 3.79 | 24 | -4.40% |
| 47 | ShimadzuCorporation, Japan | 1.97 | 3.38 | 14 | 68.40% |
| 48 | NovoNordisk A/S, Denmark | 5.86 | 3.33 | 16 | -44.30% |
| 49 | Illumina,Inc., United States of America (USA) | 3.2 | 3.22 | 17 | -1.40% |
| 50 | RoyalDutch Shell plc (Shell), Netherlands | 1.88 | 3.22 | 15 | 67.80% |
| 51 | JoelLtd., Japan | 2.42 | 3.13 | 24 | 26.50% |
| 52 | Centerfor Nanotechnology GmbH (CeNTech GmbH), Germany | 2.95 | 3.09 | 17 | 2.60% |
| 53 | ChinaElectronics Technology Group Corporation (CETC), China | 1.97 | 3.06 | 12 | 52.20% |
| 54 | AgilentTechnologies, Inc., United States of America (USA) | 3.3 | 3.03 | 15 | -10.10% |
| 55 | MitsubishiGroup, Japan | 3.69 | 3.01 | 20 | -20.30% |
| 56 | ChinaNational Chemical Corporation (ChemChina), China | 4.67 | 2.86 | 13 | -40.10% |
| 57 | GeneralElectric Company (GE), United States of America (USA) | 0.85 | 2.84 | 11 | 226.50% |
| 58 | UniResearch Ltd., Norway | 2.23 | 2.84 | 37 | 24.60% |
| 59 | IntelCorporation, United States of America (USA) | 2.56 | 2.83 | 19 | 8.30% |
| 60 | TechintGroup, Italy | 2.17 | 2.8 | 14 | 26.10% |
| 61 | Atmosphericand Environmental Research, Inc. (AER), United States of America (USA) | 1.14 | 2.79 | 8 | 138.50% |
| 62 | ChengduInstitute of Organic Chemistry (CIOC), CAS, China | 2.72 | 2.72 | 8 | -2.20% |
| 63 | NewEngland Biolabs, Inc. (NEB), United States of America (USA) | 3.63 | 2.68 | 7 | -27.60% |
| 64 | LockheedMartin Corporation, United States of America (USA) | 2.87 | 2.58 | 18 | -12.00% |
| 65 | SynfuelsChina Technology Co., Ltd., China | 1.23 | 2.57 | 15 | 104.00% |
| 66 | SociedadEuropea de Análisis Diferencial de Movilidad SL (SEADM), Spain | – | 2.56 | 4 | N/A |
| 67 | D-WaveSystems, Inc., Canada | – | 2.5 | 4 | N/A |
| 68 | H3Biomedicine Inc., United States of America (USA) | 2.58 | 2.47 | 7 | -6.50% |
| 69 | SaudiBasic Industries Corporation (SABIC), Saudi Arabia | 1.76 | 2.46 | 8 | 36.80% |
| 70 | WatersCorporation, United States of America (USA) | 3.27 | 2.45 | 9 | -26.60% |
| 71 | JohnsonMatthey (JM), United Kingdom (UK) | 2.12 | 2.45 | 11 | 13.40% |
| 72 | HumanLongevity, Inc., United States of America (USA) | 3.67 | 2.44 | 8 | -35.00% |
| 73 | AbbottLaboratories, United States of America (USA) | – | 2.33 | 3 | N/A |
| 74 | TotalS.A., France | 2.08 | 2.33 | 13 | 9.60% |
| 75 | PortugueseOncology Institute (IPO), Portugal | 0.99 | 2.31 | 32 | 128.30% |
| 76 | CelgeneCorporation, United States of America (USA) | 0.8 | 2.3 | 7 | 183.60% |
| 77 | D.E. Shaw Research, United States of America (USA) | 0.08 | 2.3 | 5 | 2598.10% |
| 78 | RigakuCorporation, Japan | 2.48 | 2.27 | 13 | -10.10% |
| 79 | XanaduQuantum Technologies Inc., Canada | 0.25 | 2.25 | 3 | 781.30% |
| 80 | CorningIncorporated, United States of America (USA) | 0.26 | 2.21 | 6 | 743.10% |
| 81 | HRLLaboratories LLC, United States of America (USA) | 2.63 | 2.19 | 4 | -18.50% |
| 82 | TataGroup, India | 0.2 | 2.17 | 12 | 971.00% |
| 83 | CortevaAgriscience, United States of America (USA) | – | 2.14 | 3 | N/A |
| 84 | Jacobs,United States of America (USA) | 2.25 | 2.09 | 20 | -9.00% |
| 85 | SouthAustralian Water Corporation (SA Water), Australia | 2.23 | 2.06 | 6 | -9.60% |
| 86 | HaldorTopsøe A/S, Denmark | 2.14 | 2.03 | 7 | -7.10% |
| 87 | BiogenInc., United States of America (USA) | 6.96 | 2 | 15 | -71.80% |
| 88 | DropsensSL, Spain | 1 | 2 | 2 | 95.80% |
| 88 | Novilytic,LLC, United States of America (USA) | – | 2 | 2 | N/A |
| 88 | PiramalEnterprises Limited, India | – | 2 | 2 | N/A |
| 89 | AustrianCentre of Industrial Biotechnology (ACIB), Austria | 2.1 | 1.97 | 9 | -8.10% |
| 90 | OSRAMLicht AG, Germany | 0.54 | 1.94 | 6 | 250.90% |
| 91 | WellspringBiosciences, United States of America (USA) | – | 1.9 | 2 | N/A |
| 92 | OtsukaHoldings Co., Ltd., Japan | 0.49 | 1.9 | 14 | 280.40% |
| 93 | ChinaNational Tobacco Company (CNTC), China | 3.29 | 1.88 | 10 | -44.10% |
| 94 | GlobalFoundriesInc., United States of America (USA) | 0.63 | 1.84 | 4 | 185.40% |
| 95 | PeptideInstitute, Inc., Japan | 0.88 | 1.83 | 2 | 105.20% |
| 96 | PacificBiosciences of California, Inc., United States of America (USA) | 1.08 | 1.75 | 12 | 59.20% |
| 97 | EisaiCo., Ltd., Japan | 2.27 | 1.74 | 13 | -24.80% |
| 98 | SinopecCorporation, China | 1.7 | 1.69 | 26 | -2.70% |
| 99 | WellingtonLaboratories Inc., Canada | 0.67 | 1.69 | 3 | 145.80% |
| 100 | KWHWater B.V., Netherlands | 1.46 | 1.67 | 10 | 12.40% |
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