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与胆管癌相关的MAGEH1基因编码功能描述

2022.8.05
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zhaoqisun

致力于为分析测试行业奉献终身

该基因属于黑色素瘤相关抗原(MAGE)超家族的非CT(非癌症/睾丸)亚群。编码蛋白可能与细胞凋亡、细胞周期停滞、生长抑制或细胞分化有关。该蛋白可能通过STAT1α(信号转导子和转录激活子1α)途径参与ATRA(全反式维甲酸)信号传导。
This gene belongs to the non-CT (non cancer/testis) subgroup of the melanoma-associated antigen (MAGE) superfamily. The encoded protein is likely associated with apoptosis, cell cycle arrest, growth inhibition or cell differentiation. The protein may be involved in the atRA (all-trans retinoic acid) signaling through the STAT1-alpha (signal transducer and activator of transcription 1-alpha) pathway.

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