neil3属于细菌fpg/nei家族的一类dna糖基化酶。这些糖基化酶通过切割活性氧损伤的碱基并通过相关的裂合酶反应引入DNA链断裂来启动碱基切除修复的第一步（Bandaru等人，2002【PubMed 12509226】。
NEIL3 belongs to a class of DNA glycosylases homologous to the bacterial Fpg/Nei family. These glycosylases initiate the first step in base excision repair by cleaving bases damaged by reactive oxygen species and introducing a DNA strand break via the associated lyase reaction (Bandaru et al., 2002 [PubMed 12509226]).[supplied by OMIM, Mar 2008]
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