PDE4D基因编码的功能和结构描述

这个基因编码四个哺乳动物对应的果蝇“dunce”基因中的一个。编码蛋白具有3'，5'-环腺苷酸磷酸二酯酶活性，降解camp，在多种细胞类型中充当信号转导分子。该基因使用不同的启动子产生多个交替剪接的转录变体，编码功能蛋白。

This gene encodes one of four mammalian counterparts to the fruit fly 'dunce' gene. The encoded protein has 3',5'-cyclic-AMP phosphodiesterase activity and degrades cAMP, which acts as a signal transduction molecule in multiple cell types. This gene uses different promoters to generate multiple alternatively spliced transcript variants that encode functional proteins.