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实体肿瘤检测BRIP1基因介绍

2022.9.06
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zhaoqisun

致力于为分析测试行业奉献终身

该基因编码的蛋白质是recq-deah螺旋酶家族的成员,与乳腺癌1型(brca1)的brct重复序列相互作用。结合复合体在1型乳腺癌(brca1)正常双链断裂修复功能中起重要作用。这个基因可能是生殖系癌症诱发突变的靶点。

The protein encoded by this gene is a member of the RecQ DEAH helicase family and interacts with the BRCT repeats of breast cancer, type 1 (BRCA1). The bound complex is important in the normal double-strand break repair function of breast cancer, type 1 (BRCA1). This gene may be a target of germline cancer-inducing mutations.

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