●Chemosphere（IF=8.943）Early hematopoietic injury triggered by benzene characterized with inhibition of erythrocyte differentiation involving the mollicutes_RF39-derived citrulline. (2022)

●Cellular and Molecular Gastroenterology and Hepatology（IF=8.797）The Critical and Diverse Roles of CD4^–CD8^– Double Negative T Cells in Nonalcoholic Fatty Liver Disease.(2022)

●Clinical Nutrition（IF=7.643）Dietary inflammatory potential mediated gut microbiota and metabolite alterations in Crohn''s disease: A fire-new perspective.（2022）

非靶向代谢组项目文章

●Nature Communications（IF=17.694）Cardiac disruption of SDHAF4-mediated mitochondrial complex II assembly promotes dilated cardiomyopathy.（2022）

●Nature Communications（IF=17.694）Neddylation inhibition induces glutamine uptake and metabolism by targeting CRL3^SPOP E3 ligase in cancer cells. (2022)

●Advanced Science （IF=17.521）Hepatic Suppression of Mitochondrial Complex II Assembly Drives Systemic Metabolic Benefits. (2022)

●Science Advances（IF=14.957）Liver cancer heterogeneity modeled by in situ genome editing of hepatocytes.（2022）

●Gut microbes（IF=9.434）Integrative metagenomic and metabolomic analyses reveal gut microbiota-derived multiple hits connected to development of gestational diabetes mellitus in humans. （2022）

●Biological Procedures Online（IF=7.717）Clinical Prognostic Factors and Integrated Multi-Omics Studies Identify Potential Novel Therapeutic Targets for Pediatric Desmoid Tumor.（2022）

● Gut（IF=31.793）Mapping the human gut mycobiome in middle-aged and elderly adults: multiomics insights and implications for host metabolic health.（2022）

●Phytomedicine（IF=6.656）Integrated hepatic single-cell RNA sequencing and untargeted metabolomics reveals the immune and metabolic modulation of Qing-Fei-Pai-Du decoction in mice with coronavirus-induced pneumonia. (2022)

●Frontiers in Nutrition（IF=6.59）Intestinal Microbiota and Serum Metabolic Profile Responded to Two Nutritional Different Diets in Mice. (2022)

●Cancer Cell International （IF=6.429）YY1 promotes pancreatic cancer cell proliferation by enhancing mitochondrial respiration.（2022）

●Frontiers in Cell and Developmental Biology（IF=6.081）Protein Expression Landscape Defines the Formation Potential of Mouse Blastoids From EPSCs. （2022）

Q200宏代谢项目文章

●Military Medical Research（IF=34.915）Oral administration of asparagine and 3-indolepropionic acid prolongs survival time of rats with traumatic colon injury.（2022）

●Science Translational Medicine（IF=19.319）Risk assessment with gut microbiome and metabolite markers in NAFLD development.（2022）

●Microbiome（IF=16.837）Altered gut metabolites and microbiota interactions are implicated in colorectal carcinogenesis and can be non-invasive diagnostic biomarkers.（2022）

●Microbiome（IF=16.837）Gut microbiota-derived ursodeoxycholic acid from neonatal dairy calves improves intestinal homeostasis and colitis to attenuate extended-spectrum β-lactamase-producing enteroaggregative Escherichia coli infection.（2022）

●Microbiome（IF=16.837）Gut microbiome mediates the protective effects of exercise after myocardial infarction.（2022）

●npj Parkinson’s Disease（IF= 9.304）Plasma branched-chain and aromatic amino acids correlate with the gut microbiota and severity of Parkinson’s disease.（2022）

●Frontiers in Nutrition（IF=6.59）Protective Effects of Intestinal Gallic Acid in Neonatal Dairy Calves Against Extended-Spectrum β-lactamase Producing Enteroaggregative Escherichia coli Infection: Modulating Intestinal Homeostasis and Colitis.（2022）

●Frontiers in Nutrition（IF=6.59）Metagenomic and metabolomic analyses show correlations between intestinal microbiome diversity and microbiome metabolites in ob/ob and ApoE^-/- mice.（2022）

●Frontiers in Microbiology（IF=6.064）Temporal Changes in Fecal Unabsorbed Carbohydrates Relative to Perturbations in Gut Microbiome of Neonatal Calves: Emerging of Diarrhea Induced by Extended-Spectrum β-lactamase-Producing Enteroaggregative Escherichia coli.（2022）

●Frontiers in Pharmacology（IF=5.988）Fermented Rosa Roxburghii Tratt Juice Alleviates High-Fat Diet-Induced Hyperlipidemia in Rats by Modulating Gut Microbiota and Metabolites.（2022）

胆汁酸项目文章

●Nature Communications（IF=17.694）The gut microbiota-bile acid axis links the positive association between chronic insomnia and cardiometabolic diseases.（2022）

●Nature Communications（IF=17.694）Disulfiram ameliorates nonalcoholic steatohepatitis by modulating the gut microbiota and bile acid metabolism.（2022）

●Advanced Science（IF=17.521）Hepatic Suppression of Mitochondrial Complex II Assembly Drives Systemic Metabolic Benefits.（2022）

●Science Advances（IF=14.957）Liver cancer heterogeneity modeled by in situ genome editing of hepatocytes.（2022）

●ISME Journal（IF=11.217）Genome-centric investigation of bile acid metabolizing microbiota of dairy cows and associated diet-induced functional implications.（2022）

●Gut microbes（IF=9.434）Cholecystectomy-induced secondary bile acids accumulation ameliorates colitis through inhibiting monocyte/macrophage recruitment.（2022）

●Cellular and Molecular Gastroenterology and Hepatology（IF= 8.797）Hepatic Reduction in Cholesterol 25-Hydroxylase Aggravates Diet-induced Steatosis.（2022）

●Frontiers in Cellular and Infection Microbiology（IF=6.073）Comprehensive Analysis of Gut Microbiota and Fecal Bile Acid Profiles in Children With Biliary Atresia.（2022）

●Frontiers in Microbiology（IF= 6.064）The negative effect of Akkermansia muciniphila-mediated post-antibiotic reconstitution of the gut microbiota on the development of colitis-associated colorectal cancer in mice.（2022）

●Nature Aging（IF=N/A） Metagenomic and metabolomic remodeling in nonagenarians and centenarians and its association with genetic and socioeconomic factors.（2022）

其他方法项目文章

●代谢流/ Science Translational Medicine（IF=19.319）SERAC1 is a component ofthe mitochondrial serine transporter complex required forthe maintenance of mitochondrial DNA.（2022）

●代谢流/ Nature Communications（IF=17.694）Blocking glycine utilization inhibits multiple myeloma progression by disrupting glutathione balance.（2022）

● 脂质组/ Journal of Hematology & Oncology（IF=23.168）Mammary adipocytes protect triple‑negative breast cancer cells from ferroptosis.（2022）

●脂质组/ Theranostics（IF=11.6）SCD1/FADS2 fatty acid desaturases equipoise lipid metabolic activity and redox-driven ferroptosis in ascites-derived ovarian cancer cells.（2022）

●脂质组/ Journal of Biological Chemistry（IF=5.486）Polyunsaturated fatty acids promote the rapid fusion of lipid droplets in Caenorhabditis elegans.（2022）

●能量代谢/ ACS Applied Materials & Interfaces（IF=10.383）Dual Inhibitions on Glucose/Glutamine Metabolisms for Nontoxic Pancreatic Cancer Therapy.（2022）

●脂肪酸/ Frontiers in Immunology（IF= 8.786）Metabolomics Signature and Potential Application of Serum Polyunsaturated Fatty Acids Metabolism in Patients With Vitiligo.（2022）

●脂肪酸/ Biomedicine & Pharmacotherapy（IF=7.419）The methyltransferase METTL3-mediated fatty acid metabolism revealed the mechanism of cinnamaldehyde on alleviating steatosis. （2022）

●脂肪酸/ Chinese Journal of Traumatology（IF=N/A）The role of altered fatty acid in pathological scars and their dermal fibroblasts.（2022）

●甜味剂靶向定量/ Nutrients（IF=6.706）The Associations between Maternal Serum Aspartame and Sucralose and Metabolic Health during Pregnancy.（2022）

●短链脂肪酸/ Frontiers in Cellular and Infection Microbiology（IF=6.073）Probiotic Cocktail Alleviates Intestinal Inflammation Through Improving Gut Microbiota and Metabolites in Colitis Mice.（2022）

●短链脂肪酸/ Frontiers in Microbiology（IF=6.064）The negative effect of Akkermansia muciniphila-mediated post-antibiotic reconstitution of the gut microbiota on the development of colitis-associated colorectal cancer in mice.（2022）

2022年虽挑战重重，但这份“成绩单”收获满满。在2023年，祝愿各位科研工作者继续攻坚克难、大展宏兔。

新

春

献

礼

Happy New Year

新春献礼，元气开年！请在文末留言区写下您的新春祝福、新年愿望或对麦特绘谱的祝福，绘谱将精选获赞最多的前30位精彩留言赠送新年定制版《贾伟教授手书·日历》一份。

日历展示

合

集

推

荐

● 肠病合集

● 肝病合集

● 肿瘤合集

● 非靶向合集

麦特绘谱生物科技（上海）有限公司（Metabo-Profile）汇聚了从事代谢组学和转化医学研究近二十年的海内外专家团队，专注于精准医学和健康领域的高端代谢组学技术服务及科研、临床试剂盒产品研发，业务覆盖临床、动物、细胞、微生物、药物、食品及营养等领域，是一家集科技服务、健康检测及产品研发于一体的国家级高新技术企业。

成立至今，麦特绘谱已为上千家三甲医院、科研院所和企业提供高端、定制化的代谢组学一站式整体解决方案，协助客户与合作伙伴发表SCI文章200+篇，累计影响因子2000+，包括Cell Metabolism、Immunity、Gut、Diabetes Care、Advanced Science、Hepatology、Microbiome、Nature Communications等领域内权威期刊。