赛默飞世尔UltiMate3000钛系统高效液相色谱的设计和诞生是为了消除和解决由铁及其它过渡金属离子对分离柱、样品和溶剂所造成的污染而引起 的各种问题，尤其是在分离过程中能保持蛋白质的完整性和其在翻译修饰后的稳定性，UltiMate3000能与赛默飞世尔的领先产品ProSwift、 ProPac和 DNAPac离子分离柱配合使用，钛系统高效液相色谱的流路是由钛金属、陶瓷和高性能的聚合物所构成的，因此即使在高盐、强酸、强碱的恶劣条件下，系统也 能可靠和长时间地工作，并延长系统的使用寿命。赛默飞世尔UltiMate3000钛系统高效液相色谱是一套完全生物兼容的系统，为以蛋白质、多肽、抗体 和核 (苷)酸为基础的药品研发提供了一套完整的分析工具。

指标参数 
Gradient Formation: Single quaternary or dual ternary ，low pressure gradient 
Flow Rate Range: 1–10,000 µL/min isocratic; ，up to 6000 µL/min gradient 
Flow Rate Precision: <0.1% RSD at 1 mL/min 
System Pressure Range: 0.1–35 MPa (5000 psi) 
pH Range: 1–13 
Sample Capacity: 3x well-plate-sized sample containers and 15 × 10 mL vials for reagents, diluents, and transport liquids 
Injection Volume: 0.1–250 &micro;L, depending on loop and syringe 
Injection Methods: Full-loop, partial-loop, microliter pickup, and user-defned injection procedures 

Fractionation Modes: Time slices, peak signal, manual trigger, external trigger 
Fractionation Containers: 96 and 384 (deep) well plates (un)capped vials, 0.3-10.0 mL 
Delay Volume: 15 &micro;L 

Sample Thermostatting: From 4 to 45 °C 
Column Compartment: Foced-air design with up to two biocompatible 10-port switching valves 
Column Thermostatting: From 5 to 70 °C 
UV Detection: Variable wavelength or diode array detector with biocompatible analytical or semi-micro fow cells 
Wetted Parts: Titanium, sapphire, ruby, PEEK, PTFE, UHMW polyethylene, Tefzel &reg;, Tefon&reg; AF, PPS, zirconium oxide, aluminum oxide, PCTFE 

Software Control: Chromeleon Chromatography Data System provides full control and traceability for all components and automated diagnostic tests 
GLP Features: System wellness monitoring and recording of all system parameters in audit trail by Chromeleon software; Tracking system for columns, lamps, and fow cells; Automated instrument qualifcation (AutoQ&trade;) with qualifcation period monitoring