应用 |
A specific inhibitor of the mitochondrial ATP-synthase. |
产品介绍 |
Oligomycin is a macrolide that acts as a specific inhibitor of the mitochondrial ATP-synthase and blocks oxidative phosphorylation. The compound is a mixture of isomers A ,B , and C .Cancer cell studies show that Oligomycin does not activate the hypoxia-induced factor, however, it enhances the bioenergetic adaptation of heterogeneous bioenergetically organized cells. Oligomycin has been shown to decreased the cyclin D1 protein expression levels |
备注 |
该产品为A, B 和 C的混合物 |
生化机理 |
Macrolide antibiotic; inhibits mitochondrial ATPase and phosphoryl group transfer. |
别名 |
Oligomycin;Oligomycin a, b, c mixture |