AKR1C3 antibody
Cat.#: S0094
Rabbit Polyclonal Antibody
Clone ID: polyclonal
Swiss Prot: P42330
Mol Weight: 36.86kDa
Size: 100ug

Description
This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. These enzymes catalyze the conversion of aldehydes and ketones to their corresponding alcohols by utilizing NADH and/or NADPH as cofactors. The enzymes display overlapping but distinct substrate specificity. This enzyme catalyzes the reduction of prostaglandin (PG) D2, PGH2 and phenanthrenequinone (PQ), and the oxidation of 9alpha,11beta-PGF2 to PGD2. It may play an important role in the pathogenesis of allergic diseases such as asthma, and may also have a role in controlling cell growth and/or differentiation. This gene shares high sequence identity with three other gene members and is clustered with those three genes at chromosome 10p15-p14. [provided by RefSeq]

Recommended Applications
WB, ICC

Applications and Recommended Dilution Factors
WB:
ICC:

Species Reactivity
Human

Other species have not been tested

Products Data 

 

Sample (30ug of whole cell lysate)
A: Hep G2
10% SDS PAGE
diluted at 1:1000
Immunohistochemical analysis of paraffin-embedded NCI-N87 xenograft, using AKR1C3 antibody at 1:100 dilution.

Specificity
261 - 323 of Human AKR1C3

Storage Condition and Buffer
1XPBS, 40% Glycerol (pH7). 0.01% Thimerosal was added as a preservative. Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. Purified by antigen-affinity chromatography.

Alternative Names
AKR1C3 antibody, DD3 antibody, DDX antibody, HA1753 antibody, HAKRB antibody, HAKRe antibody, HSD17B5 antibody, KIAA0119 antibody, PGFS antibody, hluPGFS antibody, Aldo-keto reductase family 1 member C3 antibody, Trans-1,2-dihydrobenzene-1,2-diol dehydrogenase antibody