AKT3 Antibody(T447)
Cat.#: T1936
Rabbit Polyclonal Antibody
Clone ID: polyclonal
Swiss Prot: Q9Y243
Mol Weight: 56kDa
Size: 100ug

Description
AKT3 is a member of the AKT, also called PKB, serine/threonine protein kinase family. AKT kinases are known to be regulators of cell signaling in response to insulin and growth factors. They are involved in a wide variety of biological processes including cell proliferation, differentiation, apoptosis, tumorigenesis, as well as glycogen synthesis and glucose uptake. This kinase has been shown to be stimulated by platelet-derived growth factor (PDGF), insulin, and insulin-like growth factor 1 (IGF1).

Recommended Applications
WB, ELISA

Applications and Recommended Dilution Factors
WB: 1:50~100
ELISA: 1:1,000

Species Reactivity
Human

Products Data

 
Western blot analysis of AKT3 (arrow) using rabbit polyclonal AKT3 Antibody (T447). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the AKT3 gene (Lane 2) (Origene Technologies).

Specificity
This AKT3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide corresponding to amino acid residues surrounding T447 of human AKT3.

Storage Condition and Buffer
Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. Purified rabbit polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is first purified by protein A affinity chromatography, followed by peptide affinity purification.

Alternative Names
AKT3 antibody, DKFZp434N0250 antibody, PKB-GAMMA antibody, PKBG antibody, PRKBG antibody, RAC-PK-gamma antibody, RAC-gamma antibody, STK-2 antibody, RAC-gamma serine/threonine-protein kinase antibody, RAC-PK-gamma antibody, STK-2 antibody

Description References
Xu, Z., et al., Biochem. Biophys. Res. Commun. 312(2):388-396 (2003).
Tiwari, G., et al., Mol. Cancer Res. 1(6):475-484 (2003).
Brozinick, J.T. Jr., et al., Diabetes 52(4):935-941 (2003).
Deregibus, M.C., et al., J. Biol. Chem. 277(28):25195-25202 (2002).
Brodbeck, D., et al., J. Biol. Chem. 276(31):29550-29558 (2001).