Alpha-2C adrenergic receptor antibody
Cat.#: S0960
Rabbit Polyclonal Antibody
Clone ID: polyclonal
Swiss Prot: P18825
Mol Weight: 49.53kDa
Size: 100ul

Description
Alpha-2-adrenergic receptors are members of the G protein-coupled receptor superfamily. They include 3 highly homologous subtypes: alpha2A, alpha2B, and alpha2C. These receptors have a critical role in regulating neurotransmitter release from sympathetic nerves and from adrenergic neurons in the central nervous system. The mouse studies revealed that both the alpha2A and alpha2C subtypes were required for normal presynaptic control of transmitter release from sympathetic nerves in the heart and from central noradrenergic neurons. The alpha2A subtype inhibited transmitter release at high stimulation frequencies, whereas the alpha2C subtype modulated neurotransmission at lower levels of nerve activity. This gene encodes the alpha2C subtype, which contains no introns in either its coding or untranslated sequences. [provided by RefSeq]

Recommended Applications
WB

Applications and Recommended Dilution Factors
WB: 1:500-1:3000

Species Reactivity
Human

Other species have not been tested

Products Data

Sample (30ug of whole cell lysate)
A: Hela
10% SDS PAGE
Alpha-2C adrenergic receptor antibody
diluted at 1:1000

Specificity
Synthetic peptide contain a sequence corresponding to a region within amino acids 318 and 379 of Alpha-2C adrenergic receptor

Storage Condition and Buffer
0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative. Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. Purified by antigen-affinity chromatography.

Alternative Names
ADRA2C antibody, ADRA2L2 antibody, ADRA2RL2 antibody, ADRARL2 antibody, ALPHA2CAR antibody, Alpha-2C adrenergic receptor antibody, Alpha-2 adrenergic receptor subtype C4 antibody, Alpha-2C adrenoreceptor antibody