ADAMTS18 Antibody(C-term)
Cat.#: T3553
Rabbit Polyclonal Antibody
Clone ID: polyclonal
Swiss Prot: Q8TE60
Mol Weight: 135kDa
Size: 100ug

Description
ADAMTS18 is a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. ADAMTS family members share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. This protein has a high sequence similarity to the protein encoded by gene ADAMTS16, another family member. It is thought to function as a tumor suppressor.

Recommended Applications
WB, IHC, ELISA

Applications and Recommended Dilution Factors
WB: 1:100~500
IHC: 1:50~100
ELISA: 1:1,000

Species Reactivity
Human, Mouse

Products Data 

 

Western blot analysis of ADAMTS18 Antibody (C-term) in mouse liver tissue lysates (35ug/lane). ADAMTS18 (arrow) was detected using the purified Pab.
Formalin-fixed and paraffin-embedded human brain tissue reacted with ADAMTS18 Antibody (C-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.

Specificity
This ADAMTS18 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1073~1103 amino acids from the C-terminal region of human ADAMTS18.

Storage Condition and Buffer
Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Alternative Names
ADAMTS18 antibody, ADAMTS21 antibody, A disintegrin and metalloproteinase with thrombospondin motifs 18 antibody, antibody

Description References
Zeng,W., et.al., Biochim. Biophys. Acta 1760 (3), 517-524 (2006)
Jin,H., et.al., Oncogene 26 (53), 7490-7498 (2007)