ADAM10 antibody
Cat.#: 5141-1
Rabbit Monoclonal Antibody
Clone ID: EPR5622
Swiss Prot: O14672
Mol Weight: 100/85/65kDa
Size: 100ul

Description
Members of the ADAM family are cell surface proteins with a unique structure possessing both potential adhesion and protease domains. ADAM10 is a ADAM family member that cleaves many proteins including TNF-alpha and E-cadherin (1).

Recommended Applications
WB, IP

Applications and Recommended Dilution Factors
WB: 1:1,000 - 10,000
IP: 1:10 - 100

Species Reactivity
Human, Mouse, Rat

Species cross-reactivity is based on WB analysis.

Products Data

Western blot analysis on (A) Jurkat, (B) RAW 264.7, (C) LnCaP, and (D) MCF-7 cell lysates using anti-ADAM10 RabMAb (cat. #5141-1).

Specificity
A synthetic peptide corresponding to residues on the C-terminus in human ADAM10 was used as an immunogen.

Storage Condition and Buffer
Store at -20° C. Buffer: 50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

Alternative Names
ADAM10 antibody, AD10 antibody, CD156c antibody, HsT18717 antibody, MADM antibody, kuz antibody, Disintegrin and metalloproteinase domain-containing protein 10 antibody, CDw156 antibody, Kuzbanian protein homolog antibody, Mammalian disintegrin-metalloprotease antibody

Description References
1. Entrez Gene: gene-centered information at NCBI. Nucleic Acids Res. 2005 Jan 1;33:D54-8.