Product Specification Alternative Name: N-[2-(Methylamino)ethyl]-5-isoquinolinesulfonamide . 2HCl Formula: C12H15N3O2S·2HCl MW: 338.3 Purity: 99% (TLC) Appearance: White to off-white solid. CAS: 113276-94-1 Solubility: Soluble in DMSO (25mg/ml) and ethanol/water (1:1, 25mg/ml). Shipping: AMBIENT Long Term Storage: +4°C Use/Stability: Store, as supplied, at 0-4°C for up to 1 year. Store solutions at -20°C for up to 3 months. Replaces Prod. #: ALX-270-067 H-8 inhibits PKA and PKG selectively over PKC and MLCK (IC50’s=1.2μM, 0.48μM, 15μM and 68μM respectively). It also inhibits myosin light chain kinase.
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