Replaces Prod. #: ALX-380-030 Macrolide antibiotic that acts as a potent and selective inhibitor of vacuolar-type H+-ATPase (V-type) (IC50=004-0.4nmol/mg). Valuable tool for distinguishing among different types of ATPases. Inhibitor of endosomal acidification.¨Blocks lysosomal cholesterol trafficking in macrophages. Blocks pH regulation in brain cells. Product Specification Formula: C35H58O9 MW: 622.8 Purity: ≥95% (HPLC) Appearance: Colorless oil. CAS: 88899-55-2 Solubility: Soluble in 100% ethanol, methanol or DMSO. Shipping: SHIPPED ON BLUE ICE Long Term Storage: -20°C Use/Stability: Stable for at least 1 year after receipt when stored at -20°C. Stock solutions are stable for up to 3 months at -20°C. Hazard: TOXIC. Handling: Protect from light.
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