Replaces Prod. #: ALX-350-001
Activates adenylate cyclase by directly interacting with the catalytic unit of the enzyme leading to an increase in the intracellular concentration of cAMP. Widely used tool for the investigation of the role of cAMP as a second messenger with a broad range of potential therapeutic applications. Inotropic agent and vasodilator. Induces platelet aggregation. Inhibits ion channels by a mechanism that does not involve cAMP. Non-competitive inhibitor of nicotinic acetylcholine receptors. A negative control compound, 1,9-Dideoxyforskolin, is also available (Prod. No. BML-CN104).
Product Specification
Alternative Name: Colforsin
Formula: C22H34O7
MW: 410.5
Purity: ≥99% (TLC)
Appearance: White solid.
CAS: 66575-29-9
MI: 14: 2476
Source/Host: Isolated from Coleus forskohlii.
Solubility: Soluble in ethyl acetate (10mg/ml), anhydrous DMSO (5mg/ml) or 100% ethanol (6mg/ml). DMSO is the recommended solvent for activation of cAMP.
Shipping: AMBIENT
Long Term Storage: -20°C
Use/Stability: Stock solutions in DMSO are stable for up to 4 months when stored at +4°C. Do not dissolve in ethanol, which inhibits forskolin activation of adenylate cyclase.
Hazard: IRRITANT.