订购电话:021-51870956 在线QQ:470003480 快来www.haoranbio.com体验在线订购给您带来的快捷和方便吧! Triciribine is a synthetic tricyclic nucleoside which acts as a specific inhibitor of the Akt signaling pathway. It selectively inhibits the phosphorylation and activation of Akt1, -2 and -3 but does not inhibit Akt kinase activity nor known upstream Akt activators such as PI 3-Kinase and PDK1. It inhibits cell growth and induces apoptosis preferentially in cells that express aberrant Akt1. In whole cells triciribine is phosphorylated by adenosine kinase which may be necessary for its activity. Product Specification Formula: C13H16N6O4 MW: 320.3 Purity: ≥98% (HPLC) Appearance: Pale yellow solid CAS: 35943-35-2 Solubility: Soluble in DMSO Shipping: AMBIENT Long Term Storage: -20°C