订购电话:021-51870956 在线QQ:470003480 快来www.haoranbio.com体验在线订购给您带来的快捷和方便吧! BML-EI373-0010 10 mg INQUIRE ZM-447439 is a potent and selective inhibitor of Aurora B kinase (IC50=50nM), Aurora A and C are inhibited at higher concentrations (IC50=1000nM and 250nM respectively). Other kinases such as Cdk1 and PLK1 are not inhibited (up to 10mM). Cells treated with ZM-447439 progress through interphase, enter mitosis and assemble bipolar spindles but chromosome alignment, segregation and cytokinesis all fail. Product Specification Formula: C29H31N5O4 MW: 513.6 Purity: ≥98% (TLC) CAS: 331771-20-1 Solubility: Soluble in DMSO (25 mg/ml). Shipping: AMBIENT Long Term Storage: +20°C Use/Stability: Store solutions at -20°C for up to 3 months.
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