| Catalogue Number | ANT-295 |
| Synonyms | MDU2, MDU3, MIC4, CDW44, CSPG8, HCELL, HUTCH-I, Phagocytic glycoprotein I, PGP-1, Extracellular matrix receptor-III, ECMR-III, Hermes antigen, Hyaluronate receptor, Heparan sulfate proteoglycan, Epican) CDw44. |
| Type | Rat Anti Mouse Monoclonal. |
| Introduction | CD44 is a cell-surface glycoprotein that plays a role in cell-cell interactions, cell adhesion and migration. CD44 is a receptor for hyaluronic acid and also interacts with other ligands, such as osteopontin, collagens, and matrix metalloproteinases. CD44 participates in a wide variety of cellular functions such as lymphocyte activation, recirculation and homing, hematopoiesis, and tumor metastasis.
CD44 and CD49d are putative activity markers and CD44 a potential novel therapeutic target in multiple sclerosis. Increased CD44 antigen is associated with relapses in non-small cell lung cancers. |
| Clone | mCD44. |
| Immunogen | CD44 enriched mouse LN T cells. |
| Ig Subclass | Rat IgG. |
| Purification Method | Protein A. |
| Protein concentration | 1mg/ml in PBS (after reconstitution). |
| Storage Procedures | Lyophilized: store at 4°C. After reconstitution, if not intended for use within a month, aliquot and store at -20°C. |
| Reconstitution | Reconstitute with of H20. Mix gently, wash the sides of the vial and wait 30-60 seconds before use. Stability / Shelf LifeTwo years lyophilized, one month in solution at 4°C. |
| Antibody Properties | Staining, immunohistochemistry. For staining, use 10 µl/106 cells. Titer for IH should be determined by the investigator. |
| Available Conjugates | This antibody is also available unconjugated and conjugated to biotin. |
| Usage | Prospec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals. |
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