PJ34:原理_价格_参数_使用方法-耗材谱::分析测试百科网

溶解性	DMSO 28 mg/mL Water <1 mg/mL Ethanol <1 mg/mL
存贮条件	储存温度-20°C

产品介绍	PJ34是PARP-l/2抑制剂，EC50为20 nM。
生化机理	PJ34 inhibited peroxynitrite-induced cell necrosis with EC50 of 20 nM. PJ34 provides cardioprotection by decreasing myocardial infarct size and enhancing postischemic regional and global functional recovery .Treatment with PJ34 increased NIS promoter activity without affecting PARP-1 binding to the promoter sequence, in addition to an increase of histone modification activation marks (H3K9K14ac, H3K4me3) .
别名	PJ-34;PJ 34; N-(6-氧代-5,6-二氢菲啶-2-基)-2-(N,N-二甲基氨基)乙酰胺;PJ-34;PJ 34;N-(6-Oxo-5,6-dihydrophenanthridin-2-yl)-2-(N,N-dimethylamino)acetamide

上海阿拉丁生化科技股份有限公司