产品描述
| 熔点 | 143-145° |
| 溶解性 | Soluble in water (25 mg/ml), methanol (50 mg/ml), and ethanol (8 mg/ml). |
| 应用 | An angiotensin-converting enzyme inhibitor. |
| 产品介绍 | Enalapril Maleate是Enalapril的活性代谢物，与血管紧张素I竞争性结合到血管紧张素转换酶上，抑制血管紧张素I向血管紧张素II的转化。 |
| 备注 | Enalapril Maleate, the active metabolite of enalapril, competes with angiotensin I for binding at the angiotensin-converting enzyme, blocking the conversion of angiotensin I to angiotensin II. |
| 生化机理 | Enalapril Maleate is an effective and potent nonsulfhydryl ACE(angiotenson-converting enzyme) inhibitor. The compound has been used to study diabetic angiopathy in diabetic rats and inhibition of ACE in hog plasma (I50=1.2nM). ACE inhibitors disturb the enin-angiotensin- aldosterone system. Additional ACE inhibitors include: Enalapril, Enalaprilat dihydrate, Enalaprilat , and Enalapril-d5 Maleate Salt, among others. |
| 别名 | 依那普利马来酸盐;1-[N-[(S)-1-乙氧基羰基-3-苯丙基]-L-丙氨酰基]-L-脯氨酸马来酸盐 ;马来酸依那普利;(S)-N-[1-(Ethoxycarbonyl)-3-phenylpropyl]-Ala-Pro maleate salt;1-[N-[(S)-1-Ethoxycarbonyl-3-phenylpropyl]-L-alanyl]-L-proline Maleate;Enalapril maleate salt |
