产品描述
| 熔点 | 180-182°C |
| 溶解性 | DMSO 89 mg/mL Water <1 mg/mL Ethanol <1 mg/mL |
| 存贮条件 | 储存温度-20°C |
| 应用 | An angiotensin II receptor antagonist |
| 产品介绍 | Olmesartan Medoxomil水解产物为Olmesartan，是一种选择性AT1亚型血管紧缩素II受体拮抗剂。 |
| 备注 | Olmesartan medoxomil is a compound which is hydrolyzed to olmesartan that is a selective AT1 subtype angiotensin II receptor antagonist. |
| 生化机理 | Olmesartan Medoxomil is an angiotensin II receptor (AT1) antagonist. This compound also inhibits the negative regulatory feedback on renin secretion. The result of receptor inhibition is vasodilation and a reduction in peripheral resistance. |
| 别名 | 奥美沙坦酯; 2,3-二羟基-2-丁烯基-4-(1-羟基-1-甲基乙基)-2-丙基-1-[4-(2-1H-四唑-5-苯基)苄基]咪唑-5-羧酸酯环-2,3-碳酸酯;Olmetec; Benicar; CS 866;4-(1-Hydroxy-1-methylethyl)-2-propyl-1-[[2'-(1H-tetazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-1H-imidazole-5-carboxylic acid (5-Methyl-2-oxo-1,3-dioxol-4-yl)methyl ester |
