产品描述
| 存贮条件 | 储存温度-20°C |
| 应用 | A cell-permeable aminopropanediol immunosuppressive agent that displays lymphocyte sequestration properties. |
| 产品介绍 | Fingolimod (FTY720) HCl是一种1-磷酸-神经鞘氨醇S1P受体拮抗剂，IC50为0.33 nM。 |
| 备注 | Fingolimod (FTY720) is a S1P antagonist with IC50 of 0.033 nM. |
| 生化机理 | FTY720 is an aminopropanediol cell-permeable EDG-1 (endothelial differential gene 1 receptor) antagonist and immunosuppresive agent. It has been shown to display lymphocyte, or white blood cell, sequestration properties. When FTY720 is phosphorylated, it becomes an agonist for four sphingosine 1-phosphate receptors. FTY720 is an inhibitor of cPLA2. |
| 别名 | FTY720;盐酸芬戈莫德;FTY720;Fingolimod hydrochloride;2-Amino-2-[2-(4-octyl-phenyl)-ethyl]-propane-1,3-diol hydrochloride |
