产品描述
| 溶解性 | DMSO 113 mg/mL Water 0.001 mg/mL Ethanol 2 mg/mL |
| 存贮条件 | 储存温度-20°C |
| 产品介绍 | Bosentan Hydrate是一种内皮素(ET)受体拮抗剂，靶点有ET-A和ET-B，Ki分别为4.7 nM和95 nM。 |
| 备注 | Bosentan is an endothelin (ET) receptors antagonist for ET-A and ET-B with Ki of 4.7 nM and 95 nM, respectively. |
| 生化机理 | Bosentan is a competitive and dual antagonist of endothelin-1 at the endothelin-A (ET-A) and endothelin-B (ET-B) receptors. |
| 别名 | 波生坦(水合物); N-[6-(2-羟基乙氧基)-5-(2-甲氧基苯氧基)-2-嘧啶-2-基-嘧啶-4-基]-4-叔丁基苯磺酰胺水合物;4-(1,1-Dimethylethyl)-N-(6-(2-hydroxyethoxy)-5-(2-methoxyphenoxy)(2,2'-bipyrimidin)-4-yl)benzenesulfonamide monohydrate;Benzenesulfonamide |
