产品描述
| 溶解性 | Soluble in water (<1.2 mg/ml), ethanol (≥50 mg/ml), DMSO (≥50 mg/ml), DMF, and methanol. |
| 存贮条件 | 储存温度-20°C |
| 应用 | a melatonin MT1/MT2 receptor agonist. |
| 产品介绍 | Ramelteon是一种新型的的Melatonin受体激动剂，作用于人MT1和MT2受体及小鸡前脑Melatonin受体，Ki值分别为14 pM， 112 pM和23.1 pM。 |
| 备注 | Ramelteon is a novel melatonin receptor agonist for human MT1 and MT2 receptors and chick forebrain melatonin receptors with Ki of 14 pM, 112 pM and 23.1 pM, respectively. |
| 生化机理 | Ramelteon is a melatonin MT1/MT2 receptor (MEL-1A-R/MEL-1B-R) agonist. |
| 别名 | TAK-375;雷美替胺; 瑞美替昂; (S)-N-[2-(1,6,7,8-四氢-2H-茚并[5,4-b]呋喃-8-基)乙基]丙酰胺;TAK-375;Rozerem;TAK375;TAK 375;(S)-N-[2-(1,6,7,8-Tetrahydro-2H-indeno-[5,4-b]furan-8-yl)ethyl]propionamide |
