溶解性 | DMSO |
存贮条件 | 储存温度-20°C |
生化机理 |
MK-2894, a highly potent and selective second generation EP4 antagonist.MK-2894 exhibits favorable pharmacokinetic profile in a number of preclinical species and potent anti-inflammatory activity in several animal models of pain/inflammation. MK-2894 also shows favorable GI tolerability profile in rats when compared to traditional NSAID indomethacin. |