产品描述
| 敏感性 | 对湿度敏感 |
| 溶解性 |
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| 存贮条件 | 储存温度2-8℃ |
| 应用 | Gallamine Triethiodide is a synthetic nondepolarizing blocking drug. Target: mAChR Gallamine triethiodide is a non-depolarising muscle relaxant. It acts by combining with the cholinergic receptor sites in muscle and competitively blocking the transmitter action of acetylcholine. Gallamine triethiodide has a parasympatholytic effect on the cardiac vagus nerve which causes tachycardia and occasionally hypertension. Very high doses cause histamine release. Gallamine triethiodide is commonly used to stabilize muscle contractions during surgical procedures. From Wikipedia. |
| 产品介绍 | Gallamine Triethiodide是胆碱能受体抑制剂和非去极化阻断剂，IC50为68.0±8.4 μM。 |
| 备注 | Gallamine triethiodide(Flaxedil) is a cholinergic receptor blocker with an IC50 of 68.0 ± 8.4 μM. |
| 生化机理 | Muscle relaxant; allosteric muscarinic receptor antagonist with an order of potency of M2 > M1 = M4 > M3 = M5. Ligand for the peripheral anionic binding site of acetylcholinesterase. |
| 别名 | 三碘季铵酚; 2-[2,6-双(2-三乙基铵乙氧基)苯氧基]乙基三乙基铵三碘化物;2-[2,6-Bis(2-triethylazaniumylethoxy)phenoxy]ethyl-triethylazanium triiodide |
