溶解性 | Soluble in acetone, chloroform, ethanol (4 mg/ml), DMSO (10 mg/ml), and water (50 mM). |
存贮条件 | 储存温度-20°C |
应用 | A selective acetylcholinesterase inhibitor |
产品介绍 | Galanthamine是长效中枢活性乙酰胆碱酯酶(AChE)抑制剂,IC50为410 nM,同时是神经元烟碱乙酰胆碱受体的变构增强剂。 |
生化机理 | Galanthamine is a selective acetylcholinesterase inhibitor that blocks the breakdown of acetylcholine, allowing receptors to be activated for longer periods of time. |
别名 | 加兰他敏; 11-甲基-3-甲氧基-4a,5,9,10,11,12-六氢-6H-苯并呋喃[3a,3,2ef][2]苯并氮杂卓-6-醇;(4aS,6R,8aS)-4a,5,9,10,11,12-Hexahydro-3-methoxy-11-methyl-6H-benzofurol[3a,3,2,-ef][2]benzazepin-6-ol |