产品描述
| 溶解性 | Soluble in DMSO (63 mg/ml at 25 °C), ethanol (18 mg/ml at 25 °C), methanol, acetone, and water (0.5 mg/ml). |
| 存贮条件 | 储存温度-20°C |
| 应用 | A selective inhibitor of Cox-2 |
| 产品介绍 | Valdecoxib is a prescription NSAID exhibiting anti-inflammatory, analgesic, and antipyretic properties. Valdecoxib inhibits prostaglandin synthesis via Cox-2 inhibition and is used in the treatment of osteoarthritis and theumatoid arthritis. Valdecoxib selectively inhibits Cox-2 (IC50 of 0.005 μM) over Cox-1 (IC50 of 140 μM). |
| 备注 | Valdecoxib is a potent and selective inhibitor of COX-2 with IC50 of 5 nM. |
| 别名 | SC-65872, YM-974;伐地考昔;4-(5-甲基-3-苯基-1,2-恶唑-4-基)苯磺酰胺;Bextra;SC 65872;4-(5-Methyl-3-phenyl-1,2-oxazol-4-yl)benzenesulfonamide |
