溶解性 |
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存贮条件 | 储存温度-20°C |
应用 | a positive allosteric modulator (PAM) of mGluR-4 |
产品介绍 | VU 0364439是mGlu4阳性变构调节剂(PAM),EC50为19.8 nM。 |
生化机理 | VU 0364439 is a very potent positive allosteric modulator (PAM) of mGluR-4 (metabotropic glutamate receptor) (EC50 = 19.8 nM in vitro for human mGluR-4). Drug candidate for Parkinson's disease, anxiety, and pain. |
别名 | VU0364439; VU-0364439;N-[3-氯-4-[[(2-氯苯基)氨基]磺酰基]苯基]-2-吡啶甲酰胺;VU0364439; VU-0364439; N-[3-Chloro-4-[[(2-chlorophenyl)amino]sulfonyl]phenyl]-2-pyridinecarboxamide |