熔点 | 217°C |
敏感性 | 对光敏感 |
溶解性 | Soluble in water (>25 mg/ml), and DMSO (50 mM) |
存贮条件 | 储存温度2-8°C |
应用 | An inhibitor of ST and SLC6A2. |
产品介绍 | Venlafaxine hydrochloride 是一种5-羟色胺-去甲肾上腺素再摄取抑制剂(SNRI)。 |
备注 | Venlafaxine is an arylalkanolamine serotonin-norepinephrine reuptake inhibitor (SNRI). |
生化机理 | Venlafaxine Hydrochloride is a dual ST and SLC6A2 (serotonin and noradrenalin re-uptake) inhibitor that displays ~ 30-fold higher affinity for ST (SERT) (Ki = 82 nm) than SLC6A2 (NET) (Ki = 2480 nM). |
别名 | 盐酸万拉法新;盐酸文拉法辛;1-[2-(二甲胺)-1-(4-甲氧苯基)乙基]环己醇盐酸盐;1-[2-(Dimethylamino)-1-(4-methoxyphenyl)ethyl]cyclohexanol Hydrochloride; Wy 45030 hydrochloride; Effexor hydrochloride |