产品描述
| 熔点 | 209-214℃ |
| 溶解性 | Soluble in water (slightly), acetone (~10 mg/ml), DMSO (52 mg/ml at 25 °C), methanol (~10 mg/ml), and ethanol (50 mg/ml). |
| 存贮条件 | 储存温度2-8℃ |
| 应用 | A non steroidal anti-inflammatory agent found to inhibit COX-2 isoenzymes |
| 产品介绍 | Tolfenamic Acid是一种COX-2抑制剂，IC50为0.2 μM。 |
| 备注 | Tolfenamic acid is a COX-2 inhibitor with IC50 of 0.2 μM. |
| 生化机理 | Tolfenamic Acid is non steroidal anti-inflammatory agent found to inhibit COX-2 isoenzymes in dogs. Its analgesic property is due to activation of Ca2+-activated K+ channels. |
| 别名 | 托芬那酸;N-(3-氯-2-甲苯基)邻氨基苯甲酸;2-[(3-氯-2-甲基苯基)氨基]苯甲酸;2-(3-氯-2-甲基苯胺)苯甲酸;2-[(3-氯-o-甲苯氨基)苯甲酸;;Clotam;N-(3-Chloro-2-methylphenyl)anthranilic Acid;2-(3-Chloro-o-toluidino)benzoic Acid;2-[(3-Chloro-2-methylphenyl)amino]benzoic Acid; |
