产品描述
| 熔点 | 265°C |
| 敏感性 | 对光和空气敏感 |
| 溶解性 | Soluble in 1 M hydrochloric acid (50 mg/ml), water (0.84 g/l at 20 °C), alcohol, DMSO (~4 mg/ml), DMF (~1.6 mg/ml), PBS(pH=7.2) (~1.7 mg/ml), methanol, water (1.7 mg/ml at 25 °C), and ethanol (31 mg/ml at 25 °C). Insoluble in diethyl ether, and n-octan |
| 存贮条件 | 储存温度 2-8°C ,充氩储存 |
| 应用 | 5-氨基水杨酸是一种适用于 ELISA 分析的过氧化物酶底物。该底物生成棕色的可溶性终产物，该产物可通过分光光度法在 450nm 处读取。加入 3N NaOH 可终止反应，然后在 550nm 处进行读取。 |
| 产品介绍 | Mesalamine是一种抗炎化合物。 |
| 备注 | Mesalamine is an anti-inflammatory compound. |
| 生化机理 | 5-Aminosalicylic Acid, the metabolite of sulphasalazine, has been shown to inhibit PGDH (prostaglandin 15-hydroxydehydrogenase) in human placenta and bovine lung. Further studies show that this antiinflammatory compound also inhibits leukotriene formation in human leukocytes. Additionally, 5-Aminosalicylic acid demonstrates the ability to disrupt TNFα (tumor necrosis factor α)-stimulated NFκB (nuclear factor κB) activation via inhibition of the multimeric IκB kinase regulating complex. |
| 别名 | 5-AS;5-氨基-2-羟基苯甲酸;氨水杨酸;美沙拉秦;5-氨基-2-羟基苯甲酸;3-羧基-4-羟基苯胺;5-Amino-2-hydroxybenzoic acid;5-AS;Mesalamine;Mesalazine;5-Amino-2-hydroxybenzoic Acid |
