熔点 | 175-176℃ |
溶解性 |
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存贮条件 | 储存温度-20°C |
应用 | A strong norepinephrine reuptake inhibitor and weak serotonin reuptake inhibitor |
备注 | Amoxapine is a tricyclic dibenzoxazepine (an N-aryl piperazine) which acts similarly to several other tricyclic antidepressants, amoxapine inhibits GLYT2a transport activity with IC50 of 92 μM. |
生化机理 | inhibits uptake of norepinephrine; inhibits 5-HT2 serotonergic receptors. |
别名 | 阿莫沙平;2-氯-11-(1-哌嗪基)二苯并[b,f][1,4]氧氮杂卓;2-Chloro-11-(1-piperazinyl)dibenzo[b,f][1,4]oxazepine; 8-chloro-6-piperazin-1-ylbenzo[b][1,4]benzoxazepine |