产品描述
| 敏感性 | 对热敏感 |
| 溶解性 | Soluble in chloroform (50 mg/ml), DMF (~0.5 mg/ml), DMSO (50 mM), water (<1 mg/ml at 25 °C), and ethanol (10 mM, with warming). |
| 存贮条件 | 储存温度2-8℃ |
| 应用 | A traizole antifungal agent |
| 产品介绍 | Itraconazole is a triazole antifungal agent. It inhibits the fungal CYP(cytochrome P450) oxidase-mediated synthesis of ergosterol. Itraconazole also acts as an effective hedgehog signaling inhibitor in a Ptch-independent manner, presumably by binding smoothened (Smo) at a site distinct from that targeted by cyclopamine and SAG. Itraconazole is an inhibitor of CYP3A4. |
| 备注 | Itraconazole is a triazole antifungal agent. |
| 别名 | 亚特那唑;依他康唑;斯皮仁诺;4-[4-[4-[4-[[2-(2,4-二氯苯基)-2-(1H-1,2,4-三唑-1-基甲基)-1,3-二氧戊环-4-基]甲氧基]苯基]-1-哌嗪基]苯基]-2,4-二氢-2-(1-甲基丙基)-3H-1,2,4-三唑-3-酮;伊曲康唑;Oriconazole;R51211;Sporanox |
