产品描述
| 溶解性 | Soluble in DMSO (50 mg/ml at 25 °C), water (<1 mg/ml at 25 °C), ethanol (50 mg/ml at 25 °C), and chloroform. |
| 应用 | A hyperlipidemic agent. |
| 产品介绍 | Gemfibrozil 是一种降低血脂水平的化合物。 |
| 备注 | Gemfibrozil (Lopid) is a compound used to lower lipid levels. |
| 生化机理 | Gemfibrozil is a hyperlipidemic agent that elevates plasma HDL and lowers triglycerides and LDL by stabilizing apoA-I mRNA transcripts. It was found to inhibit inducible nitric oxide synthase by inhibiting the activation of nuclear factor-kappaB, activator protein-1 and CCAAT/enhancer-binding protein β. |
| 别名 | 吉非罗齐;2,2-二甲基-5-(2,5-二甲基苯氧基)戊酸;Lopid; CI-719;2,2-Dimethyl-5-(2,5-dimethylphenoxy)pentanoic Acid;2,2-Dimethyl-5-(2,5-dimethylphenoxy)valeric Acid;5-(2,5-Dimethylphenoxy)-2,2-dimethylpentanoic aci |
